The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 19, 2021

Filed:

Oct. 03, 2017
Applicant:

Canon U.s.a., Inc., Melville, NY (US);

Inventors:

Daisuke Yamada, Cambridge, MA (US);

Jeffrey Chen, Winchester, MA (US);

Badr Elmaanaoui, Belmont, MA (US);

Assignee:

Canon U.S.A., Inc., Melville, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); G01B 9/02 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0035 (2013.01); A61B 5/0066 (2013.01); A61B 5/0071 (2013.01); A61B 5/0086 (2013.01); A61B 5/6852 (2013.01); G01B 9/0203 (2013.01); G01B 9/02091 (2013.01); G01N 21/6458 (2013.01); A61B 2560/0223 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/228 (2013.01); A61B 2576/00 (2013.01); G01B 9/02067 (2013.01); G01N 21/6486 (2013.01); G01N 2021/6465 (2013.01); G01N 2021/6484 (2013.01); G01N 2201/127 (2013.01);
Abstract

A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle α formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle α at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(α). The calibration factor g(α) is a function of the angle α calculated at two or more of the plurality of locations. The angle α is composed of a transversal angle αand an axial angle α.


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