The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

May. 22, 2020
Applicants:

The Governing Council of the University of Toronto, Toronto, CA;

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Sachdev S. Sidhu, Toronto, CA;

Sarah L. Barker, Toronto, CA;

Orson W. Moe, Dallas, TX (US);

Makoto Kuro-o, Tochigi, JP;

Johanne Pastor, Flower Mound, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01); G01N 33/573 (2006.01); G01N 33/541 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); G01N 33/573 (2013.01); G01N 33/74 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/92 (2013.01); C07K 2319/32 (2013.01); G01N 33/541 (2013.01); G01N 2800/347 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01);
Abstract

An antibody and/or binding fragment thereof, wherein the antibody and/or binding fragment thereof comprises a light chain variable region and a heavy chain variable region, the light chain variable region comprising complementarity determining region (CDR) CDR-L3 and the heavy chain variable region comprising CDR-H1, CDR-H2 and CDR-H3, with the amino acid sequences of said CDRs comprising one or more of the sequences set forth below: CDR-L3; selected from any one of SEQ ID NOs: 123, 126-130, 142, 148 or 149; CDR-H1: SEQ ID NOs: 121 or 124; CDR-H2; SEQ ID NOs: 122 or 125; and/or CDR-H3: selected from any one of SEQ ID NOs: 196-226.


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