The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Jan. 27, 2016
Applicant:

Arterez, Inc., Metamora, MI (US);

Inventor:

Josefino B. Tunac, Oxford, MI (US);

Assignee:

ARTEREZ, INC., Metamora, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/86 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); G01N 33/86 (2013.01); G01N 2333/75 (2013.01); G01N 2333/8128 (2013.01); G01N 2333/8132 (2013.01); G01N 2400/40 (2013.01);
Abstract

A biomarker panel including a four-panel test for clotting that detects soluble fibrin (SF), thrombin-antithrombin complex (TAT), antithrombin III (ATIII), and plasminogen activator inhibitor (PAI-1). A biomarker panel including a three-panel test for glycocalyx integrity that detects syndecan-1 (SDC1), heparan sulfate (HS), and hyaluronidase (HAD). A biomarker panel including a test that detects a biomarker chosen from soluble fibrin (SF), thrombin-antithrombin complex (TAT), antithrombin III (ATIII), plasminogen activator inhibitor (PAI-1), syndecan-1 (SDC1), heparan sulfate (HS), hyaluronidase (HAD), and combinations thereof. A kit including a biomarker panel, instructions for use, materials to take and apply samples to the panel, and descriptions of biomarker levels and their meaning. Methods of detecting the presence of vascular disease, determining the stage of vascular disease, monitoring the progress of vascular disease treatments, and monitoring the efficacy of drugs during drug development.


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Tunac, Josefino. (2021). Biomarkers of vascular disease (U.S. Patent No. 11143659). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11143659

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