The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Oct. 19, 2016
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventor:

Abhijit Tarafder, Franklin, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/06 (2006.01); G01N 30/20 (2006.01); G01N 30/88 (2006.01); B01D 15/12 (2006.01); B01D 15/14 (2006.01);
U.S. Cl.
CPC ...
G01N 30/06 (2013.01); G01N 30/20 (2013.01); G01N 30/88 (2013.01); B01D 15/12 (2013.01); B01D 15/125 (2013.01); B01D 15/14 (2013.01); G01N 2030/207 (2013.01);
Abstract

A significant reduction in extra-column band broadening can be achieved by decoupling the injection system from the main solvent flow line. In addition, by decoupling the injection system from the main solvent flow line, additional components (e.g., filters, valves, etc.) can be introduced into the chromatography system without increasing the negative band broadening effects. Systems and methods herein provide not only for such decoupling but also for filtering precipitates from the system. As a result, a larger volume of sample can be injected into the present systems without compromising separation yield. In addition, an increase the column loading per batch, an increase the overall yield of separations, and greater system efficiency (i.e., less time lost for cleaning and maintenance) can be realized.


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