The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Jul. 22, 2020
Applicant:

Jiangnan University, Wuxi, CN;

Inventors:

Jing Wu, Wuxi, CN;

Dan Wu, Wuxi, CN;

Xin Gao, Wuxi, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/38 (2006.01); C12N 15/80 (2006.01); A23L 33/21 (2016.01); A23C 9/12 (2006.01); C12N 15/81 (2006.01); C12N 15/66 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2471 (2013.01); A23L 33/21 (2016.08); C12Y 302/01023 (2013.01); A23C 9/1206 (2013.01); C12N 15/66 (2013.01); C12N 15/81 (2013.01);
Abstract

The present invention discloses a β-galactosidase mutant, and a preparation method and application thereof, belonging to the fields of gene engineering and enzyme engineering. Amino acids of specific sites in the β-galactosidase are mutated, the β-galactosidase is transferred into a recombinant bacterium, and enzymatic transformation is performed under optimized conditions, so that the yield of galactooligosaccharide produced by the mutant reaches 59.8%, which is increased by about 70% as compared with that of wild enzyme, thereby implementing the increase of the galactooligosaccharide yield. The present invention has very high industrialized application value.


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