The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 12, 2021
Filed:
Nov. 04, 2016
Universidad DE Zaragoza, Saragossa, ES;
Centro DE Investigacion Biomedica En Red (Ciber), Madrid, ES;
Luis J. Fernández Ledesma, Saragossa, ES;
Rosa Monge Prieto, Saragossa, ES;
Guillermo Llamazares Prieto, Saragossa, ES;
José María Ayuso Domínguez, Saragossa, ES;
María Virumbrales Muñoz, Saragossa, ES;
Jorge Santolaria Mazo, Saragossa, ES;
Ignacio Ochoa Garrido, Madrid, ES;
UNIVERSIDAD DE ZARAGOZA, Saragossa, ES;
CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (CIBER), Madrid, ES;
Abstract
The present invention relates to a novel microfluidic device and a microfluidic system for culturing cell samples based on: one or more culture wells () forming cell housing volumes for three-dimensional cell culture; one or more capillary channels () for circulating cells and/or fluid media, said channels () being connected to the wells () as well perfusion means; and an inlet port () and an outlet port (') for seeding cells and/or for circulating fluid in said channel (), said ports (′) being connected to the ends of each capillary channel (). The novel configuration of the ports (′) and their corresponding channels () allows known microfluidic perfusion media to be improved, dispensing with the use of complex elements for injecting the fluid media, such as syringe pumps, for example. The invention also allows two-dimensional and three-dimensional culture studies to be performed simultaneously.