The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 12, 2021
Filed:
Apr. 05, 2018
Applicant:
Universität Stuttgart, Stuttgart, DE;
Inventors:
Roman Fischer, Nuremberg, DE;
Roland Kontermann, Nuremberg, DE;
Klaus Pfizenmaier, Tiefenbronn, DE;
Martin Siegemund, Stuttgart, DE;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/525 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/525 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to a tumor necrosis factor receptor (TNFR) binding protein complex comprising 12 or more protein ligands (PLs) that specifically bind to the extracellular part of the same TNFR. Preferably, the TNFR binding protein complex binds to the extracellular part of TNFR2. Preferably, the TNFR binding protein complex of the present invention further comprises two or more polymerization domains (PD).