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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11142557 B1

PDFFull Text
Date of Patent:
Oct. 12, 2021

Filed:

Oct. 28, 2016

Long-acting fgf21 fusion proteins and pharmaceutical composition comprising same

Applicant:

Yuhan Corporation, Seoul, KR;

Inventors:

Jun Hwan Kim, Seoul, KR;

Seyoung Lim, Yongin-si, KR;

Minji Seo, Seoul, KR;

Hyun Ho Choi, Suwon-si, KR;

Dohoon Kim, Yongin-si, KR;

Mi Kyeong Ju, Suwon-si, KR;

Ju-Young Park, Seoul, KR;

Byung Hyun Choi, Suwon-si, KR;

Jun Kyung Lee, Suwon-si, KR;

Jong Gyun Kim, Anyang-si, KR;

Su Youn Nam, Seoul, KR;

Assignee:

YUHAN CORPORATION, Seoul, KR;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Christine J Saoud

Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/50 (2006.01); A61P 1/16 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/50 (2013.01); A61P 1/16 (2018.01); A61P 3/04 (2018.01); A61P 3/10 (2018.01); A61K 38/1825 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention provides a fusion protein comprising an FGF21 mutant protein and an Fc region of an immunoglobulin. The fusion protein according to the present invention exhibits improved pharmacological efficacy, in vivo duration and protein stability, and a pharmaceutical composition comprising the fusion protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver disease or non-alcoholic steatohepatitis.

Find Patent Forward Citations

Kim, Jun. (2021). Long-acting fgf21 fusion proteins and pharmaceutical composition comprising same (U.S. Patent No. 11142557). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11142557

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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