The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Feb. 01, 2018
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Bayer Aktiengesellschaft, Leverkusen, DE;

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Timothy A. Lewis, Cambridge, MA (US);

Xiaoyun Wu, Cambridge, MA (US);

Heidi Greulich, Cambridge, MA (US);

Matthew Meyerson, Boston, MA (US);

Manuel Ellermann, Berlin, DE;

Philip Lienau, Berlin, DE;

Knut Eis, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Charlotte Christine Kopitz, Falkensee, DE;

Martin Lange, Berlin, DE;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/10 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 413/10 (2013.01); A61P 35/02 (2018.01);
Abstract

The present invention features improved compounds, especially the compound having the structure (1). Compositions and methods of identifying patients having cancer using biomarkers (e.g., PDE3A, PDE3B, SLFN12 and/or CREB3L1) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention.


Find Patent Forward Citations

Lewis, Timothy. (2021). Compounds, compositions and methods for cancer treatment (U.S. Patent No. 11142522). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11142522

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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