The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Aug. 29, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Varghese John, Culver City, CA (US);

Patricia Spilman, Culver City, CA (US);

Barbara Jagodzinska, Culver City, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 25/28 (2006.01); C07D 233/88 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/08 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 405/10 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 413/04 (2006.01); C07D 413/10 (2006.01); C07D 417/04 (2006.01); A61K 31/4166 (2006.01); A61K 31/4178 (2006.01);
U.S. Cl.
CPC ...
C07D 233/88 (2013.01); A61P 25/28 (2018.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/08 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 405/10 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 417/04 (2013.01);
Abstract

Selected compounds, compositions, and methods for inhibiting BACE are presented that have relatively high selectivity towards APP via interaction of the inhibitor with both BACE and APP.


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