The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 12, 2021
Filed:
Mar. 29, 2017
Applicant:
Dexcel Pharma Technologies Ltd., Or-Akiva, IL;
Inventors:
Abraham J. Domb, Jerusalem, IL;
Michael Grishko, Nesher, IL;
Ezra Hanuka, Nesher, IL;
Ron Schlinger, Tel-Aviv, IL;
Tal Hagigit, Moshav Gan Yoshiya, IL;
Assignee:
DEXCEL PHARMA TECHNOLOGIES LTD., Or-Akiva, IL;
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 9/00 (2006.01); A61K 31/7036 (2006.01); C08G 63/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/0019 (2013.01); A61K 31/7036 (2013.01); C08G 63/06 (2013.01);
Abstract
A depot system containing at least one antibiotic and a biodegradable poly(ester-anhydride) of ricinoleic acid (RA) and sebacic acid (SA) having alternating or semi-alternating ester and anhydride bonds is provided. The system provides prolonged local release of the antibiotic at the site of injection while maintaining the systemic antibiotic levels at sub-therapeutic concentrations.