The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Jun. 22, 2018
Applicant:

Csl Behring Lengnau Ag, Lengnau, CH;

Inventors:

Anne Verhagen, Northcote, AU;

Sabine Pestel, Marburg, DE;

Thomas Weimer, Gladenbach, DE;

Marco Hofmann, Lahntal-Sterzhausen, DE;

Huy Huynh, Brunswick, AU;

Eugene Maraskovsky, Kew, AU;

Assignee:

CSL Behring Lengnau AG, Lengnau, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/37 (2006.01);
U.S. Cl.
CPC ...
A61K 38/37 (2013.01);
Abstract

The present invention relates to a recombinant polypeptide comprising a truncated von Willebrand Factor (VWF) capable of binding to blood coagulation Factor VIII (FVIII) for use in reducing the immunogenicity of Factor VIII (FVIII) wherein said recombinant polypeptide and a blood coagulation Factor VIII (FVIII) protein are co-administered to a subject suffering from a 10 blood coagulation disorder. The invention further relates to pharmaceutical compositions and kits for said use.


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