The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Jan. 17, 2020
Applicant:

Stealth Biotherapeutics Corp, Monaco, MC;

Inventor:

D. Travis Wilson, Newton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/06 (2006.01); A61K 38/08 (2019.01); A61K 38/07 (2006.01); C07K 5/078 (2006.01); C07K 5/09 (2006.01); C07K 5/087 (2006.01); C07K 5/107 (2006.01); C07K 5/065 (2006.01); C07K 5/113 (2006.01); C07K 5/072 (2006.01); C07K 5/097 (2006.01); A61K 47/64 (2017.01); A61K 38/05 (2006.01); A61K 38/13 (2006.01); A61K 38/17 (2006.01); A61K 38/40 (2006.01); A61K 38/44 (2006.01); A61K 38/45 (2006.01); A61K 38/46 (2006.01); A61K 38/51 (2006.01); A61K 38/53 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); A61K 38/08 (2013.01); A61K 38/13 (2013.01); A61K 38/1709 (2013.01); A61K 38/40 (2013.01); A61K 38/44 (2013.01); A61K 38/443 (2013.01); A61K 38/45 (2013.01); A61K 38/46 (2013.01); A61K 38/51 (2013.01); A61K 38/53 (2013.01); A61K 47/645 (2017.08); C07K 5/06078 (2013.01); C07K 5/06095 (2013.01); C07K 5/06156 (2013.01); C07K 5/0812 (2013.01); C07K 5/0815 (2013.01); C07K 5/0817 (2013.01); C07K 5/0821 (2013.01); C07K 5/1016 (2013.01); C07K 5/1021 (2013.01); C12Y 101/01037 (2013.01); C12Y 101/01042 (2013.01); C12Y 102/04002 (2013.01); C12Y 103/05001 (2013.01); C12Y 106/05003 (2013.01); C12Y 109/03001 (2013.01); C12Y 110/02002 (2013.01); C12Y 203/03001 (2013.01); C12Y 306/03014 (2013.01); C12Y 402/01002 (2013.01); C12Y 402/01003 (2013.01); C12Y 602/01004 (2013.01); C12Y 604/01001 (2013.01);
Abstract

Disclosed herein are methods and compositions for the treatment and/or prevention of diseases or conditions comprising administration of a therapeutic biological molecule, and/or naturally or artificially occurring derivatives, analogues, or pharmaceutically acceptable salts thereof, alone or in combination with one or more active agents (e.g., an aromatic-cationic peptide). The present technology provides compositions related to aromatic-cationic peptides linked to a therapeutic biological molecule and uses of the same. In some embodiments, the aromatic-cationic peptide comprises 2',6′-dimethyl-Tyr-D-Arg-Phe-Lys-NH, Phe-D-Arg-Phe-Lys-NH, or D-Arg-2′,6′-Dmt-Lys-Phe-NH.


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