The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2021

Filed:

Apr. 15, 2020
Applicant:

Arun Ananth Aiyer, Fremont, CA (US);

Inventor:

Arun Ananth Aiyer, Fremont, CA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61B 5/145 (2006.01); A61B 5/1495 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1455 (2013.01); A61B 5/1495 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/7246 (2013.01); A61B 2562/0238 (2013.01);
Abstract

A sensor device which is adapted for detecting target molecules in-vitro and in-vivo, comprises a MIR source for exciting the target species and a probe beam with split frequency to measure the effect of excitation. The latter uses a heterodyne interferometer operating at a beat frequency ˜ KHz. to MHz. The photo-thermal excitation of target species leads to refractive index change. The RI change produces probe beam displacement and is measured using a 1) grating heterodyne interferometer, 2) grating deflection amplifier and 3) evanescent field heterodyne interferometer. The measured RI change can be related to specie concentration change in target volume. Furthermore, a sensing method for detecting HbA1c concentration and its change with thermal excitation is described in terms of phase shift of the OCT spectrum obtained with spectral domain optical coherence tomography (SD-OCT).


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