Problem solving using quantum annealer, useful for example in sequencing, for instance nucleic acid sequencing

Abstract

Quantum annealers as analog or quantum processors can find paths in problem graphs embedded in a hardware graph of the processor, for example finding valid paths, shortest paths or longest paths. A set of input, for example nucleic acid reads, can be used to set up a graph with edges between nodes denoting overlap (i.e., common base pairs) between the reads with constraints applied to perform sequence alignment or sequencing of a nucleic acid (e.g., DNA) strand or sequence, finding a solution that has a ground state energy. At least a portion of the described approaches can be applied to other problems, for instance resource allocations problems, e.g., job scheduling problems, traveling salesperson problems, and other NP-complete problems.