The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2021

Filed:

Sep. 15, 2016
Applicant:

Immunocore Limited, Abingdon, GB;

Inventors:

Peter Eamon Molloy, Abingdon, GB;

Arsen Valeryevich Volkov, Abingdon, GB;

Dhaval Jaykant Sangani, Abingdon, GB;

Graham Anthony Hood, Abingdon, GB;

Chandramouli Reddy Chillakuri, Abingdon, GB;

Assignee:

Immunocore Limited, Abingdon, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C12N 15/10 (2006.01); C07K 14/725 (2006.01); C07K 14/74 (2006.01); C12N 15/66 (2006.01); C12N 15/85 (2006.01); C40B 40/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1072 (2013.01); C07K 14/7051 (2013.01); C07K 14/70539 (2013.01); C12N 15/1062 (2013.01); C12N 15/1086 (2013.01); C12N 15/66 (2013.01); C12N 15/85 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C12N 2015/8518 (2013.01); C12N 2015/8527 (2013.01); C40B 40/02 (2013.01); C40B 40/10 (2013.01);
Abstract

The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain comprising an alpha chain variable domain and a beta chain comprising a beta chain variable domain and the library comprises more than one TRAV gene product and/or more than one TRBV gene product, wherein the beta chain variable domain does not comprise one or more of a TRBV5-1, 5-3, 5-4, 5-5, 5-6, 5-7 or 5-8 gene product and wherein the plurality of TCRs do not consist essentially of TCRs comprising a TRAV12-2 gene product from a natural repertoire and a TRBV6 gene product from a natural repertoire and TCRs comprising a TRAV21 gene product from a natural repertoire and a TRBV6 gene product from a natural repertoire.


Find Patent Forward Citations

Loading…