The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Oct. 13, 2017
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Aravive Biologics, Inc., Houston, TX (US);
Amato J. Giaccia, Stanford, CA (US);
Erinn Bruno Rankin, Redwood City, CA (US);
Jennifer R. Cochran, Stanford, CA (US);
Douglas Jones, Newton, MA (US);
Mihalis Kariolis, Stanford, CA (US);
Katherine Cynthia Fuh, St. Louis, MO (US);
Yu Miao, Sunnyvale, CA (US);
Susan Hershenson, Palo Alto, CA (US);
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, Stanford, CA (US);
ARAVIVE BIOLOGICS, INC., Houston, TX (US);
Abstract
Compositions and methods are provided for alleviating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits activity of AXL, MER or Tyro3 protein activity, for example by competitive or non-competitive inhibition of the binding interaction between AXL, MER or Tyro3 and its ligand GAS6.