The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Apr. 06, 2018
Applicant:
Api Corporation, Tokyo, JP;
Inventors:
Makoto Hibi, Kyoto, JP;
Jun Ogawa, Kyoto, JP;
Ryoma Miyake, Kanagawa, JP;
Hiroshi Kawabata, Kanagawa, JP;
Assignee:
API CORPORATION, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 1/20 (2006.01); C12P 13/04 (2006.01); C12P 17/12 (2006.01); C12P 17/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0071 (2013.01); C12N 1/20 (2013.01); C12P 13/04 (2013.01); C12P 17/10 (2013.01); C12P 17/12 (2013.01); C12Y 114/00 (2013.01); C12Y 114/11006 (2013.01); H05K 999/99 (2013.01);
Abstract
The present invention provides a pipecolic acid 4-hydroxylase protein exemplified by the following (A), (B), and (C), having activity to react with L-pipecolic acid in the presence of 2-oxoglutaric acid and iron(II) ions to produce trans-4-hydroxy-L-pipecolic acid, and a method for producing 4-hydroxy amino acid, which method comprises reacting the pipecolic acid 4-hydroxylase protein, cells containing the protein, a treated product of the cells, and/or a culture liquid obtained by culturing the cells, with α-amino acid to produce 4-hydroxy amino acid: