The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Apr. 07, 2015
The General Hospital Corporation, Boston, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Martin Yarmush, Newton, MA (US);
Basak E. Uygun, Cambridge, MA (US);
Korkut Uygun, Cambridge, MA (US);
Maria-Louisa Izamis, Boston, MA (US);
Alejandro Soto-Gutierrez, Boston, MA (US);
Herman Tolboom, Zurich, CH;
Hiroshi Yagi, Brookline, MA (US);
Carley Shulman, Sudbury, MA (US);
Jack Milwid, Denver, CO (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
One aspect of the invention provides a method for harvesting adult cells from an organ. The method includes perfusing the organ with a perfusate and isolating adult cells from the organ, thereby harvesting the adult cells from the organ. Another aspect of the invention provides a method for rehabilitating an organ. The method includes: dividing the organ into a first portion and a second portion, perfusing the first portion with a decellularization medium, isolating adult cells from the second portion, and recellularizing the first portion with a suspension of the adult cells, thereby rehabilitating the organ.