The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Oct. 28, 2016
Applicant:
Keio University, Tokyo, JP;
Inventors:
Minoru Ko, Tokyo, JP;
Tomohiko Akiyama, Tokyo, JP;
Assignee:
KEIO UNIVERSITY, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); C12N 15/09 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0662 (2013.01); C12N 5/0696 (2013.01); C12N 15/09 (2013.01); C12N 2501/60 (2013.01); C12N 2502/45 (2013.01); C12N 2503/02 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01);
Abstract
In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method using human ES/iPS cells and being stable and highly efficient. A method of inducing differentiation into a desired cell type within a short period of time and with high efficiency by attenuating differentiation resistance of a pluripotent stem cell to generate a pluripotent stem cell that actively proceeds to a differentiated cell type has been found, and thus the present invention has been completed.