The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2021

Filed:

May. 16, 2019
Applicant:

Nanjing Leads Biolabs Co. Ltd., Nanjing, CN;

Inventors:

Xiaoqiang Kang, Plainshoro, NJ (US);

Shoupeng Lai, Germantown, MD (US);

Xiao Huang, Nanjing, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01); C07K 14/55 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 9/0019 (2013.01); A61P 35/00 (2018.01); C07K 14/55 (2013.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); C07K 16/2896 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01);
Abstract

The present invention provides an isolated monoclonal antibody that specifically binds human PD-1. A nucleic acid molecule encoding the antibody, an expression vector, a host cell and a method for expressing the antibody are also provided. The present invention further provides an immunoconjugate, a bispecific molecule and a pharmaceutical composition comprising the antibody, as well as a diagnostic and treatment method using an anti-PD-1 antibody of the invention.


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