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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11136382 B1

PDFFull Text
Date of Patent:
Oct. 05, 2021

Filed:

Oct. 18, 2019

Antibodies and antibody fragments for binding to nav1.9 polypeptides and methods for using same to treat pain-related disease

Applicant:

Populas Biopharmaceutical (Wuhan) Limited, Wuhan, CN;

Inventor:

Daichang Yang, Wuhan, CN;

Assignee:

POPULAS BIOPHARMACEUTICAL (WUHAN) LIMITED, Wuhan, CN;

Attorneys:

Greer, Burns & Crain, Ltd.

Gregory P. Einhorn

Primary Examiner:

Christine J Saoud

Assistant Examiner:

Jon M Lockard

Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/624 (2013.01);
Abstract

The present invention provides an antibody or antibody fragment thereof for a targeted cytomembrane voltage-gated sodium channel α subunit Nav1.9. The specific binding target is a S3-4 ring of a voltage sensor paddle of a domain II of the voltage-gated sodium channel α subunit. The antibody or antibody fragment thereof is able to inactivate a voltage sensor valve, to make sodium ions unable to enter nerve cells normally, thereby achieving the effect of treating and relieving pains.

Find Patent Forward Citations

Yang, Daichang. (2021). Antibodies and antibody fragments for binding to nav1.9 polypeptides and methods for using same to treat pain-related disease (U.S. Patent No. 11136382). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11136382

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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