The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Mar. 23, 2018
Recombinant immunoglobulin heavy chains comprising a sortase conjugation loop and conjugates thereof
Applicant:
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Inventors:
Alfred Engel, Weilheim, DE;
Pavel Kubalec, Feldafing, DE;
Alfons Nichtl, Hohenpeissenberg, DE;
Tobias Oelschlaegel, Munich, DE;
Rainer Schlecht, Frankfurt am Main, DE;
Assignee:
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 2317/51 (2013.01); C07K 2317/522 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01);
Abstract
The disclosure describes a recombinant immunoglobulin heavy chain comprising a sortase conjugation loop, methods for conjugating and/or labeling such recombinant immunoglobulin heavy chains by use of the enzyme sortase and to the conjugates/labeled products obtained via the method.