The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
May. 01, 2019
Emory University, Atlanta, GA (US);
Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);
H. Trent Spencer, Marietta, GA (US);
Christopher B. Doering, Atlanta, GA (US);
Brantley R. Herrin, Decatur, GA (US);
Max Dale Cooper, Atlanta, GA (US);
Emory University, Atlanta, GA (US);
Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);
Abstract
This disclosure relates to recombinant cellular expression of chimeric proteins with peptide sequences derived from lymphocyte receptors and uses for treating cancer. In certain embodiments, the disclosure relates to a recombinant vector comprising a nucleic acid that encodes a chimeric protein with a segment with a targeting moiety based on a variable lymphocyte receptor (VLR) capable of binding a tumor associated antigen and a segment with a T cell signal transduction subunit. In certain embodiments, the recombinant vectors are used in immune based cancer treatments.