The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Mar. 08, 2017
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Eric Gross, Menlo Park, CA (US);
Carl Hurt, Stanford, CA (US);
Daria Mochly-Rosen, Menlo Park, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Abstract
Methods of modulating the interaction between calcineurin and a calcineurin-binding protein partner are provided. Aspects of the methods include contacting a cell with a peptidic agent that modulates the interaction between calcineurin and a TRPV channel. Also provided are pharmaceutical compositions that comprise a peptidic agent that selectively modulates the interaction between calcineurin and a calcineurin-binding protein partner. Also provided are methods of treating a condition in a subject by selectively modulating the interaction between calcineurin and a calcineurin-binding TRPV channel. Also provided are screening methods to identify candidate agents that modulate calcineurin protein-protein interactions.