The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Dec. 19, 2019
Applicants:
Tsinghua University, Beijing, CN;
South China University of Technology, Guangzhou, CN;
Inventors:
Zhanglin Lin, Guangzhou, CN;
Tingting Wang, Guangzhou, CN;
Qing Zhao, Shanghai, CN;
Xu Wang, Shanghai, CN;
Bihong Zhou, Guangzhou, CN;
Lei Xing, Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/35 (2006.01); C07K 1/14 (2006.01);
U.S. Cl.
CPC ...
C07K 14/35 (2013.01); C07K 1/14 (2013.01); C07K 2319/60 (2013.01); C07K 2319/92 (2013.01);
Abstract
The present disclosure describes a Mtu ΔI-CM intein variant containing one or more mutations or a biologically active fragment thereof, and a method for producing and purifying a molecule of interest using the intein variant. Further described are isolated fusion proteins comprising the intein variant and a tag and a molecule of interest. Also described are expression systems for expressing the intein variant as well as polypeptide screening methods employing the intein variant.