The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Mar. 15, 2018
Applicant:
Eloxx Pharmaceuticals Ltd., Rehovot, IL;
Inventors:
Michael Mizhiritskii, Rehovot, IL;
Mani Bushan Kotala, Kompally, IN;
Ravinder Palidi, Nagarkurnool, IN;
Assignee:
ELOXX PHARMACEUTICALS LTD., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/224 (2006.01); C07H 1/00 (2006.01); C07H 15/23 (2006.01);
U.S. Cl.
CPC ...
C07H 15/224 (2013.01); C07H 1/00 (2013.01); C07H 15/23 (2013.01);
Abstract
Synthetic pathways for preparing pseudo-trisaccharide aminoglycoside compounds represented by Formula I or Ia as defined in the specification and donor and acceptor compounds useful for preparing such compounds are provided. A process of stereoselectively preparing compounds represented by Formula III as defined in the specification, while avoiding chromatographic separation of stereoisomers are also provided. Compounds prepared by the described processes and uses thereof are also provided.