The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Jul. 01, 2019
Applicant:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Inventors:
Naweed Muhammad, Fremont, CA (US);
Keith R. Bley, Menlo Park, CA (US);
Assignee:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/09 (2006.01); A61K 31/661 (2006.01); A61K 47/54 (2017.01); C07C 233/25 (2006.01); C07F 9/11 (2006.01);
U.S. Cl.
CPC ...
C07F 9/096 (2013.01); A61K 31/661 (2013.01); A61K 47/548 (2017.08); C07C 233/25 (2013.01); C07F 9/11 (2013.01);
Abstract
The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.