The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2021

Filed:

Oct. 12, 2018
Applicant:

Cambrex Charles City, Inc., Charles City, IA (US);

Inventors:

Par Holmberg, Charles City, IA (US);

Lars Eklund, Charles City, IA (US);

David Adams, Charles City, IA (US);

Michael Letourneau, Charles City, IA (US);

Margus Eek, Charles City, IA (US);

Alo Soone, Charles City, IA (US);

Assignee:

CAMBREX CHARLES CITY, INC., Charles City, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/12 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
C07D 489/12 (2013.01);
Abstract

There is provided a novel process for the preparation of a compound of formula I, wherein R, R, W, Z andare as described in the description, by demethylation of a corresponding O-methyl derivative with a borohydride-based reagent. This process may be used in the preparation of buprenorphine.


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