The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Jun. 19, 2020
Applicant:
Noramco, Llc, Wilmington, DE (US);
Inventors:
Martin Benedict Strack, Kleve, DE;
Jasper Kaiser, Nijmegen, NL;
Gnel Mkrtchyan, Watkinsville, GA (US);
Wen-Chun Zhang, Bogart, GA (US);
Assignee:
Noramco, LLC, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/06 (2006.01); C07D 413/06 (2006.01); C07D 403/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/06 (2013.01);
Abstract
The present disclosure relates to the preparation of methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (ITE) and related compounds with high yield, purity, and scalability. The processes apply the use of a Weinreb amide intermediate as a scaffold for the preparation of ITE and structural analogs.