The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2021

Filed:

Oct. 23, 2015
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

The Governors of the University of Alberta, Edmonton, CA;

Inventors:

Sindy Tang, Stanford, CA (US);

Ming Pan, Stanford, CA (US);

Fengjiao Lyu, Stanford, CA (US);

Ratmir Derda, Edmonton, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C07F 7/08 (2006.01); C01B 33/18 (2006.01); C12Q 1/18 (2006.01); G01N 15/14 (2006.01); B82Y 40/00 (2011.01); B82Y 30/00 (2011.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502769 (2013.01); B01L 3/502784 (2013.01); C01B 33/18 (2013.01); C07F 7/081 (2013.01); C12Q 1/18 (2013.01); G01N 15/1404 (2013.01); G01N 15/1484 (2013.01); B01L 2200/0615 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/16 (2013.01); B01L 2300/165 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C01P 2004/62 (2013.01); C01P 2004/64 (2013.01); G01N 2015/1006 (2013.01);
Abstract

Described here is a composition comprising amphiphilic silica nanoparticles, wherein the silica nanoparticles are partially fluorinated. Also described here is a method for droplet-based assay, comprising dispersing at least one aqueous droplet in a continuous fluorous phase in a microfluidic channel, wherein at least one amphiphilic silica nanoparticle is absorbed to the interface of the continuous fluorous phase and the aqueous droplet, and wherein the silica nanoparticle is partially fluorinated. Further described here is a method for droplet-based assay, comprising dispersing at least one aqueous phase droplet in a continuous fluorous phase in a microfluidic channel, wherein the continuous fluorous phase comprises at least one partially fluorinated amphiphilic particle adsorbed to an interface of the continuous fluorous phase and the aqueous phase droplet, and wherein the aqueous phase droplet comprises at least one hydrophilic polymer adsorbed to the amphiphilic particle at the interface.


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