The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Nov. 29, 2017
Preparation of solid cyclodextrin complexes for ophthalmic active pharmaceutical ingredient delivery
Applicant:
Oculis Ehf, Reykjavik, IS;
Inventors:
Thorsteinn Loftsson, Reykjavik, IS;
Zoltan Fulop, Reykjavik, IS;
Assignee:
OCULIS SA, Lausanne, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/34 (2017.01); A61P 27/02 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/10 (2006.01); A61K 9/14 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 31/4184 (2006.01); A61K 31/573 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); A61K 47/38 (2006.01); A61K 47/40 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6951 (2017.08); A61K 9/0048 (2013.01); A61K 9/08 (2013.01); A61K 9/10 (2013.01); A61K 9/146 (2013.01); A61K 9/50 (2013.01); A61K 9/51 (2013.01); A61K 31/4184 (2013.01); A61K 31/573 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/186 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01); A61P 27/02 (2018.01); A61K 47/40 (2013.01);
Abstract
The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 μm.