The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11135280 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 05, 2021

Filed:

Mar. 27, 2017
Applicants:

Integrated Biotherapeutics, Inc., Rockville, MD (US);

Integral Molecular, Inc., Philadelphia, PA (US);

Inventors:

Mohammad Javad Aman, Rockville, MD (US);

Katie A. Howell, North Bethesda, MD (US);

Edgar Davidson, Philadelphia, PA (US);

Benjamin J. Doranz, Drexel Hill, PA (US);

Assignees:

INTEGRATED BIOTHERAPEUTICS, INC., Rockville, MD (US);

INTEGRAL MOLECULAR, INC., Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C12N 2760/14122 (2013.01); C12N 2760/14134 (2013.01);
Abstract

Provided herein are methods of incorporating substitutions of specified residues into a filovirus GP in order to increase immunogenicity and/or broaden the cross-reactivity of the protective immune response against other filovirus members. Also provided herein are mutant filovirus GPs comprising such substitutions.


Find Patent Forward Citations

Aman, Mohammad. (2021). Modified ebolavirus glycoproteins comprising mutations in the head and base domains that increase antibody cross-reactivity (U.S. Patent No. 11135280). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11135280

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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