The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2021

Filed:

Aug. 22, 2018
Applicant:

Kansas State University Research Foundation, Manhattan, KS (US);

Inventors:

Xiuzhi S. Sun, Manhattan, KS (US);

Hongzhou Huang, Manhattan, KS (US);

Tiffany L. Carter, Kansas City, MO (US);

Mark L. Weiss, Manhattan, KS (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/06 (2006.01); A61K 38/00 (2006.01); A61L 24/00 (2006.01); A61L 24/10 (2006.01);
U.S. Cl.
CPC ...
A61K 9/06 (2013.01); A61K 38/00 (2013.01); A61L 24/0031 (2013.01); A61L 24/108 (2013.01); A61L 2400/04 (2013.01); C12N 2513/00 (2013.01); C12N 2533/50 (2013.01);
Abstract

Peptide hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and optionally albumin. The peptide comprises (consists of) a terminal hydrophobic region, a central turning region, and a terminal hydrophilic region. Methods of making such hydrogels are also described, along with methods of using the hydrogels as scaffolding for tissue engineering, hemostatic agents, as well as 3-dimensional cell cultures, and for drug delivery, encapsulation of active agents (therapeutic cells, molecules, drugs, compounds), cell transplantation, cell storage, virus culture and storage.


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