The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2021
Filed:
Feb. 20, 2017
Applicant:
Sichuan Jiuzhang Biological Science and Technology Co. Ltd, Sichuan, CN;
Inventors:
Jie Zhang, Sichuan, CN;
Xiaoguang Chen, Sichuan, CN;
Nina Xue, Sichuan, CN;
Mengtian Zhang, Sichuan, CN;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/216 (2006.01); A61K 9/20 (2006.01); A61P 31/20 (2006.01); A61P 35/02 (2006.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); A61K 9/16 (2006.01); C07C 69/732 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0065 (2013.01); A61K 9/16 (2013.01); A61K 9/20 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 31/216 (2013.01); A61P 31/04 (2018.01); A61P 31/20 (2018.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07C 69/732 (2013.01);
Abstract
Provided are a use of chlorogenic acid in preparing pharmaceuticals for the inhibition of LAG-3 and a use of chlorogenic acid in preparing pharmaceuticals for the treatment of LAG-3-mediated diseases. The inhibition of LAG-3 by chlorogenic acid is useful in cancer therapy, anti-viral therapy, and sepsis treatment. The oral bioavailability of chlorogenic acid is enhanced by preparing chlorogenic acid as a gastric floating tablet.