The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Aug. 19, 2020
Applicants:

Indiana University Research and Technology Corporation, Indianapolis, IN (US);

Kent State University, Kent, OH (US);

Inventors:

Jacob T. Shelley, Troy, NY (US);

Kelsey L. Williams, Kent, OH (US);

Gary M. Hieftje, Bloomington, IN (US);

Andrew J. Schwartz, Williamsville, NY (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/14 (2006.01); G01N 27/68 (2006.01); G01N 30/72 (2006.01); G01N 21/67 (2006.01); H01J 13/16 (2006.01); H01J 15/00 (2006.01); H01J 37/32 (2006.01); H01J 37/04 (2006.01); H01J 49/16 (2006.01); H01J 49/12 (2006.01); G01N 27/622 (2021.01);
U.S. Cl.
CPC ...
H01J 49/145 (2013.01); G01N 21/67 (2013.01); G01N 27/622 (2013.01); G01N 27/68 (2013.01); G01N 30/726 (2013.01); H01J 13/16 (2013.01); H01J 15/00 (2013.01); H01J 37/04 (2013.01); H01J 37/32055 (2013.01); H01J 37/32935 (2013.01); H01J 37/32981 (2013.01); H01J 49/12 (2013.01); H01J 49/167 (2013.01); H01J 49/168 (2013.01);
Abstract

A solution-cathode glow discharge mass spectrometry (SCGD-MS) apparatus comprises a SCGD source and a mass spectrometer. The SCGD source may comprise conductive rods, a power source, and a capillary. A method for ionizing an analyte comprises flowing an electrically conductive liquid onto a conductive rod, applying an electric potential to a second conductive rod such that a plasma discharge forms between the first conductive rod and the electrically conductive liquid to produce ions, and separating the ions in a mass spectrometer. The analyte may be a polypeptide that may be contacted with trypsin. The analyte may be a solid, liquid, gas, chemical complex, or ion in solution. The method may comprise sequencing the polypeptide.


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