The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Apr. 10, 2018
Applicant:

Imperial College Innovations Limited, London, GB;

Inventors:

Anthony Edward George Cass, London, GB;

Joshua Benno Edel, London, GB;

Jasmine Y. Y. Sze, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); G01N 33/53 (2006.01); G01N 33/487 (2006.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); C12N 15/115 (2013.01); G01N 33/487 (2013.01); C12N 2310/16 (2013.01);
Abstract

THE present application relates to a method of detecting one or more analytes in a sample, the method comprising (a) providing a carrier nucleic acid molecule with at least one single-stranded region; (b) providing one or more aptamers specific for the analyte, wherein the aptamers additionally comprise a single-stranded portion complementary to at least one single-stranded region on the carrier nucleic acid; (c) contacting the carrier nucleic acid and one or more aptamers with the sample, forming a carrier nucleic acid/N aptamer/analyte complex, and; (d) detecting the presence of the carrier nucleic acid/aptamer/analyte complex.


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