The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Jul. 22, 2005
Applicants:

Parry John Guilford, Dunedin, NZ;

Natalie Jane Kerr, Dunedin, NZ;

Robert Craig Pollock, Dunedin, NZ;

Inventors:

Parry John Guilford, Dunedin, NZ;

Natalie Jane Kerr, Dunedin, NZ;

Robert Craig Pollock, Dunedin, NZ;

Assignee:

Pacific Edge Limited, Dunedin, NZ;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); G01N 33/574 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07K 14/4748 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57407 (2013.01); G01N 33/57488 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/52 (2013.01);
Abstract

Early detection of tumors is a major determinant of survival of patients suffering from tumors, including bladder tumors. Members of the BTM or UBTM family can be highly and consistently accumulated in bladder tumor tissue and other tumor tissue, and/or can be accumulated in urine of patients, and thus are markers for bladder and other types of cancer. In certain embodiments, BTMs or UBTMs can accumulate in the urine, and detection of UBTM family members can be an effective diagnostic approach. In some embodiments, quantitative PCR methods have advantages over microarray methods. In other embodiments, detection and quantification of a plurality of BTMs or UBTMs can increase the sensitivity and specificity of detection of bladder cancer, and therefore provides methods for determining the stage and type of bladder cancer. Kits provide easy, convenient ways for carrying out the methods of this invention.


Find Patent Forward Citations

Loading…