The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

May. 14, 2019
Applicants:

The Regents of the University of California, Oakland, CA (US);

Board of Trustees of Michigan State University, East Lansing, MI (US);

Inventors:

Andrew R. Hagen, Oakland, CA (US);

Cheryl A. Kerfeld, Walnut Creek, CA (US);

Nancy B. Sloan, Berkeley, CA (US);

Markus Sutter, Oakland, CA (US);

Bryan H. Ferlez, Haslett, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 14/195 (2006.01); C12N 15/62 (2006.01); C07K 1/22 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); C07K 14/315 (2006.01);
U.S. Cl.
CPC ...
C07K 14/195 (2013.01); B01D 15/363 (2013.01); B01D 15/3804 (2013.01); C07K 1/22 (2013.01); C07K 14/315 (2013.01); C12N 15/62 (2013.01); C07K 2319/70 (2013.01);
Abstract

The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair.


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