The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Oct. 18, 2012
Applicants:

Institut National DE LA Recherche Agronomique, Paris, FR;

The Royal Institution for the Advancement of Learning/mcgill University, Montreal, CA;

Inventors:

Anne Lespine, Toulouse, FR;

Roger Prichard, Toulouse, FR;

Cecile Menez, Toulouse, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/00 (2006.01); A61K 45/06 (2006.01); A61P 25/08 (2006.01); A61P 31/12 (2006.01); A61P 33/00 (2006.01); A61P 35/00 (2006.01); C07H 17/08 (2006.01); A61K 31/7048 (2006.01); A61K 31/277 (2006.01); A61K 31/365 (2006.01); A61K 31/475 (2006.01); A61K 31/366 (2006.01); C07D 493/06 (2006.01); C07D 493/20 (2006.01);
U.S. Cl.
CPC ...
C07H 17/08 (2013.01); A61K 31/277 (2013.01); A61K 31/365 (2013.01); A61K 31/366 (2013.01); A61K 31/475 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01); C07D 493/06 (2013.01); C07D 493/20 (2013.01);
Abstract

The present invention relates to the use of avermectin derivative as a drug for the treatment of parasitic infections. The avermectin derivative is represented by the formula (I) wherein: (i) Ris chosen from the group constituted of —CH(CH), —CH(CH)CHCH, or cyclohexyle, (ii) X represents —CH—CH—, or —CH═CH—, (iii) Ris chosen from the group constituted of or —OH group, (iv) Ris OH or NOH, (v) represents a single bond when Ris OH, or a double bond when Ris NOH, as an inhibitor of a membrane-bound protein which transports exogenous compounds out of target cells.


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