The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Jan. 21, 2015
Applicants:

Max-delbrueck-centrum Fuer Molekulare Medizin, Berlin, DE;

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Wolf-Hagen Schunck, Berlin, DE;

Dominik Mueller, Berlin, DE;

Robert Fischer, Berlin, DE;

Gerd Wallukat, Berlin, DE;

Anne Konkel, Berlin, DE;

John Russell Falck, Dallas, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/38 (2006.01); C07C 309/21 (2006.01); C07C 311/51 (2006.01); C07C 323/41 (2006.01); C07D 277/82 (2006.01); C07D 291/04 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07F 9/3826 (2013.01); C07C 309/21 (2013.01); C07C 311/51 (2013.01); C07C 323/41 (2013.01); C07D 277/82 (2013.01); C07D 291/04 (2013.01); C07F 9/3882 (2013.01); C07F 9/4015 (2013.01);
Abstract

The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.


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