The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2021
Filed:
Apr. 10, 2020
Applicant:
Eisai R&d Management Co., Ltd., Tokyo, JP;
Inventors:
Roch Boivin, North Chelmsford, MA (US);
Eric Carlson, Merrimack, NH (US);
Atsushi Endo, Andover, MA (US);
Hans Hansen, Somerville, MA (US);
Lynn D. Hawkins, Concord, MA (US);
Sally Ishizaka, Weston, MA (US);
Matthew Mackey, Melrose, MA (US);
Sridhar Narayan, Belmont, MA (US);
Takashi Satoh, Andover, MA (US);
Shawn Schiller, Haverhill, MA (US);
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 471/04 (2006.01); A61K 31/519 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/519 (2013.01); A61K 31/55 (2013.01); C07D 487/04 (2013.01); Y02P 20/582 (2015.11);
Abstract
Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.