The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Sep. 22, 2020
Applicant:

Vtv Therapeutics Llc, High Point, NC (US);

Inventors:

Adnan M. M. Mjalli, Oak Ridge, NC (US);

Dharma Rao Polisetti, High Point, NC (US);

Jareer Nabeel Kassis, Colfax, NC (US);

Matthew J. Kostura, Hillsborough, NC (US);

Mustafa Guzel, Jamestown, NC (US);

Otis Clinton Attucks, Winston-Salem, NC (US);

Robert Carl Andrews, Jamestown, NC (US);

Samuel Victory, Winston-Salem, NC (US);

Suparna Gupta, Waverly, IA (US);

Assignee:

vTv Therapeutics LLC, High Point, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 1/16 (2006.01); A61K 31/4168 (2006.01); A61K 31/4188 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); C07D 471/04 (2006.01); C07D 235/30 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/4168 (2013.01); A61K 31/4188 (2013.01); A61K 31/428 (2013.01); A61K 31/437 (2013.01); A61P 1/16 (2018.01); C07D 235/30 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 513/04 (2013.01);
Abstract

Substituted fused imidazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted fused imidazole derivative, and methods of use in treating renal diseases are provided. The substituted fused imidazole derivatives may control the activity or the amount or both the activity and the amount of heme-oxygenase.


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