The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Sep. 24, 2019
Applicant:

Cardurion Pharmaceuticals, Llc, Cambridge, MA (US);

Inventors:

Nobuyuki Matsunaga, Kanagawa, JP;

Yasufumi Miyamoto, Kanagawa, JP;

Junya Shirai, Kanagawa, JP;

Takashi Nakahata, Kanagawa, JP;

Zenyu Shiokawa, Kanagawa, JP;

Tomohiro Okawa, Kanagawa, JP;

Akito Shibuya, Kanagawa, JP;

Malcolm MacCoss, Seabrook Island, SC (US);

Assignee:

Cardurion Pharmaceuticals, LLC, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/505 (2006.01); A61P 9/00 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61P 9/00 (2018.01); C07D 417/14 (2013.01); C07D 498/08 (2013.01);
Abstract

The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.


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