The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2021
Filed:
Feb. 15, 2018
Applicant:
Cavion, Inc., Charlottesville, VA (US);
Inventors:
Thomas E. Richardson, Chapel Hill, NC (US);
Michelle Higgin, Apex, NC (US);
Timothy MacDonald, Charlottesville, VA (US);
Assignee:
CAVION, INC., Charlottesville, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); A61K 31/5377 (2006.01); C07D 405/12 (2006.01); A61P 25/08 (2006.01); C07D 235/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61P 25/08 (2018.01); C07D 235/14 (2013.01);
Abstract
The present disclosure describes carbamate analogs of mibefradil, as well as their compositions and methods of use. The compounds block the activity of one or more isoforms of voltage-gated calcium channels and are useful in the treatment of diseases including, e.g., cancer.