The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

May. 16, 2017
Applicant:

University of Science and Technology of China, Hefei, CN;

Inventors:

Shiyong Liu, Hefei, CN;

Guhuan Liu, Hefei, CN;

Yanyan Jiang, Hefei, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); A61K 49/00 (2006.01); C07K 14/585 (2006.01); C07K 14/765 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0019 (2013.01); A61K 49/0056 (2013.01); A61K 49/0058 (2013.01); C07K 14/585 (2013.01); C07K 14/765 (2013.01);
Abstract

A conjugate containing a fluorescent chromophore, which has any structure selected from C1 to C3. The conjugate containing the fluorescent chromophore provided by the described embodiments includes one fluorescent chromophore and two highly reactive groups R1 and R2 linked to the fluorescent chromophore by a covalent bond. The fluorescent chromophore in the conjugate initially has no or only weak fluorescence emission capability, and only after the two highly reactive groups react together with the corresponding molecule, the fluorescent chromophore has strong fluorescence emission. Therefore, the efficiency of conjugation of drug molecules to targeting molecules can be monitored in situ by the infrared fluorescence emission intensity and applied to the target-mediated drug delivery.


Find Patent Forward Citations

Liu, Shiyong. (2021). Conjugate and block copolymer containing fluorescent chromophore and preparation method therefor and use thereof (U.S. Patent No. 11129909). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11129909

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