The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2021
Filed:
Feb. 02, 2018
Applicant:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Inventors:
Longqin Hu, Belle Mead, NJ (US);
Herve Aloysius, Newburgh, NY (US);
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61P 35/00 (2006.01); A61K 31/704 (2006.01); C07K 7/02 (2006.01);
U.S. Cl.
CPC ...
A61K 47/64 (2017.08); A61K 31/704 (2013.01); A61P 35/00 (2018.01); C07K 7/02 (2013.01);
Abstract
The present disclosure is directed to a series of target-selective chemotherapeutic ester prodrugs comprising PSA-cleavable peptides that promote the delivery of free doxorubicin and other chemotherapeutic agents into the prostate and/or prostate tumors with greater efficiency.