The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2021
Filed:
Jun. 19, 2019
Ying Chen, St. Louis, MO (US);
Fumihiko Urano, St. Louis, MO (US);
Yeawon Kim, St. Louis, MO (US);
Sun-ji Park, St. Louis, MO (US);
Ying Chen, St. Louis, MO (US);
Fumihiko Urano, St. Louis, MO (US);
Yeawon Kim, St. Louis, MO (US);
Sun-Ji Park, St. Louis, MO (US);
Washington University, St. Louis, MO (US);
Abstract
Among the various aspects of the present disclosure is the provision of methods and compositions to treat or prevent an endoplasmic reticulum (ER) stress-mediated kidney disease in a subject, the method comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of an ER calcium channel stabilizing agent or an ER stress modulating agent (e.g., mesencephalic astrocyte-derived neurotrophic factor (MANF), compound K201).