The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Apr. 09, 2017
Applicant:

Aron H. Blaesi, Cambridge, MA (US);

Inventors:

Aron H. Blaesi, Cambridge, MA (US);

Nannaji Saka, Cambridge, MA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 9/20 (2006.01); B29C 64/106 (2017.01); B33Y 10/00 (2015.01); B33Y 30/00 (2015.01); B33Y 70/00 (2020.01); B33Y 80/00 (2015.01); A61K 31/167 (2006.01); A61K 31/192 (2006.01); A61K 47/10 (2017.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
A61K 9/70 (2013.01); A61K 9/2031 (2013.01); A61K 9/2072 (2013.01); A61K 31/167 (2013.01); A61K 31/192 (2013.01); A61K 47/10 (2013.01); A61K 47/34 (2013.01); B29C 64/106 (2017.08); B33Y 10/00 (2014.12); B33Y 30/00 (2014.12); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12);
Abstract

At present, the most prevalent pharmaceutical dosage forms, the oral immediate-release tablets and capsules, are granular solids. The problem of such solids is that their microstructure and properties are not predictable from physical models. As a consequence, product development and manufacture are resource-intensive and time-consuming, and quality control is statistical by testing instead of by design. Furthermore, the range of the drug release rate, and the variety of active ingredients that can be processed to a functional product, are limited in such dosage forms. Presented herein, accordingly, is a fibrous dosage form suitable for immediate-release applications prepared by a predictable liquid-based process. The fibrous dosage form includes a drug-containing solid comprising a three dimensional structural network of one or more drug-containing fibers.


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