IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11124834 B1

PDFFull Text
Date of Patent:
Sep. 21, 2021

Filed:

Dec. 03, 2018

Genetic polymorphisms associated with venous thrombosis, methods of detection and uses thereof

Applicants:

Celera Corporation, San Clemente, CA (US);

Leiden University Medical Center (Lumc) Acting on Behalf of Academic Hospital Leiden (Azl), Leiden, NL;

Inventors:

Lance Bare, Walnut Creek, CA (US);

James J. Devlin, Lafayette, CA (US);

Frits R. Rosendaal, Leiden, NL;

Pieter H. Reitsma, Leiden, NL;

Irene D. Bezemer, Leiden, NL;

Assignee:

Celera Corporation, San Juan Capistrano, CA (US);

Attorney:

Celera Corporation

Primary Examiner:

Stephen T Kapushoc

Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12P 19/34 (2006.01); C12Q 1/6883 (2018.01); A61K 31/352 (2006.01); A61K 31/4365 (2006.01); A61K 31/4439 (2006.01); A61K 31/47 (2006.01); A61K 31/60 (2006.01); A61K 31/715 (2006.01); A61K 31/727 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A61K 31/352 (2013.01); A61K 31/4365 (2013.01); A61K 31/4439 (2013.01); A61K 31/47 (2013.01); A61K 31/60 (2013.01); A61K 31/715 (2013.01); A61K 31/727 (2013.01); G01N 35/00 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); C12Q 2600/172 (2013.01);
Abstract

The present invention is based on the discovery of genetic polymorphisms that are associated with venous thrombosis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.

Find Patent Forward Citations

Loading…